Biochemistry

Globular Hemeproteins – Hemeproteins are a group of specialized proteins that contain heme as a tightly bound prosthetic group.  – The role of the heme group is dictated by the environment created by the three-dimensional structure of the protein. – For example, the heme group of a cytochrome functions as …

– In this topic, we will talk about Protein Misfolding. Protein Misfolding – Protein folding is a complex, trial-and-error process that can sometimes result in improperly folded molecules. – These misfolded proteins are usually tagged and degraded within the cell. However, this quality control system is not perfect, and intracellular …

– In the last topic in biochemistry in our website, we talked about: Primary structure of Protein , Secondary Structure of Protein. now we will discuss Tertiary structure of globular proteins. Tertiary structure of globular proteins – The primary structure of a polypeptide chain determines its tertiary structure. – “Tertiary” …

– In the last topic in Biochemistry section , we discussed The Protein Primary Structure but now we will talk about Protein Secondary Structure. Secondary structure of protein – The polypeptide backbone does not assume a random three-dimensional structure, but instead generally forms regular arrangements of amino acids that are …

– In this topic, we will discuss The Primary structure of the Protein. Primary structure of Protein – The sequence of amino acids in a protein is called the primary structure of the protein. – Understanding the primary structure of protein is important because many genetic diseases result in proteins …

Acidic and Basic Properties of Amino acids – Amino acids in aqueous solution contain weakly acidic α-carboxyl groups and weakly basic α-amino groups. – In addition, each of the acidic and basic amino acids contains an ionizable group in its side chain. – Thus, both free amino acids and some …

Structure of Amino acids – Although more than 300 different amino acids have been described in nature, only 20 are commonly found as constituents of mammalian proteins. – Each amino acid (except for proline, which has a secondary amino group) has a carboxyl group, a primary amino group, and a …